1255501-05-3Relevant academic research and scientific papers
Highly diastereo- and enantioselective organocatalytic michael addition of α-ketoamides to nitroalkenes
Basle, Olivier,Raimondi, Wilfried,Duque, Maria Del Mar Sanchez,Bonne, Damien,Constantieux, Thierry,Rodriguez, Jean
, p. 5246 - 5249 (2010)
The first organocatalytic enantio- and diastereoselective conjugate addition of α-ketoamides to nitroalkenes has been achieved using a bifunctional amino thiourea catalyst. In this new approach, the substrate amide proton plays a critical role in the form
