125564-09-2Relevant articles and documents
Evaluation of some Mannich bases of conjugated styryl ketones and related compounds versus the WiDr colon cancer in vitro
Dimmock, Jonathan R.,Phillips, Oludotun A.,Wonko, Sheri L.,Hickie, Robert A.,Tuer, Robert G.,et al
, p. 217 - 226 (2007/10/02)
The series of Mannich bases and one group of related α-aminoketones which had either 1 or 2 sites for thiol alkylation were evaluated againts the WiDr tumour in vitro.Maximum activity was found in the bis alkylating agents (12-64 times the activity of the