125564-77-4Relevant academic research and scientific papers
Functionalized organolithium compounds: Generation via reductive lithiation and nucleophilic addition to N-phenethylimides. Access to functionalized dihydropyrrolo[2,1-a]isoquinolinones
Manteca, Izaskun,Etxarri, Begona,Ardeo, Ainhoa,Arrasate, Sonia,Osante, Inaki,Sotomayor, Nuria,Lete, Esther
, p. 12361 - 12378 (2007/10/03)
A procedure for producing 1,4-dianion equivalents consists of reductive lithiation, induced by 4,4-di-tert-butylbiphenylide, of functionalized phenyl sulfides. Nucleophilic addition of 4-lithio-2-(trimelhylsilylmethyl)but-1- ene 1 and 2-(3-lithiopropyl)-2
THE CERIUM (III) MEDIATED REACTION OF TRIMETHYLSILYLMETHYL MAGNESIUM CHLORIDE WITH ESTERS AND LACTONES: THE EFFICIENT SYNTHESIS OF SOME FUNCTIONALISED ALLYLSILANES OF USE IN ANNULATION REACTIONS
Lee, Thomas V.,Channon, Julia A.,Cregg, Carmel,Porter, John R.,Roden, Frances S.,Yeoh, Helena T-L.
, p. 5877 - 5886 (2007/10/02)
The use of cerium (III) chloride alters the chemoselectivity of the reaction of trimethylsilylmethyl magnesium chloride with ester-acetals and also greatly improves the efficiency of reaction with lactones.In addition it gives improved preparations of the useful intermediates (7), (13), (18), (20) and (22) and gives direct access to the valuable functionalised allylsilanes (1) to (3) of use in annulation reactions.
