1255666-24-0 Usage
Uses
Used in Pharmaceutical Development:
2-amino-3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propanoic acid is used as a building block in the synthesis of various peptides and proteins for pharmaceutical applications. Its incorporation into peptide sequences allows for the creation of novel bioactive molecules with potential therapeutic effects.
Used in Organic Chemistry:
In the field of organic chemistry, 2-amino-3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propanoic acid serves as a versatile intermediate for the synthesis of complex organic compounds. The Boc protecting group facilitates selective reactions and can be removed under mild conditions, making it an advantageous component in multi-step synthesis processes.
Used in Research and Development:
2-amino-3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propanoic acid is utilized in research settings to explore its potential in the development of new drugs and biologically active molecules. Its unique structure and reactivity provide opportunities for investigating novel chemical reactions and mechanisms.
Used in Peptide Synthesis Industry:
2-amino-3-[1-(tert-butoxycarbonyl)piperidin-4-yl]propanoic acid is used as a key component in the synthesis of custom peptides and peptide-based therapeutics. Its presence in peptide sequences can influence the conformation, stability, and biological activity of the resulting peptides, making it an important factor in the design and synthesis of peptide drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 1255666-24-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,5,6,6 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1255666-24:
(9*1)+(8*2)+(7*5)+(6*5)+(5*6)+(4*6)+(3*6)+(2*2)+(1*4)=170
170 % 10 = 0
So 1255666-24-0 is a valid CAS Registry Number.
1255666-24-0Relevant academic research and scientific papers
Compounds and Compositions as Channel Activating Protease Inhibitors
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Page/Page column 35-36, (2008/06/13)
The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11E), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.
Solution-phase and solid-phase synthesis of novel transition state inhibitors of coagulation enzymes incorporating a piperidinyl moiety
Adang, Anton E. P.,Peters, Co A. M.,Gerritsma, Siene,De Zwart, Edwin,Veeneman, Gerrit
, p. 1227 - 1232 (2007/10/03)
2-Amino-3-piperidin-4-yl-propionic acid containing peptidomimetics are potent protease inhibitors when combined with an appropriate keto-thiazole or keto-carboxylic acid moiety. A novel P1 residue in factor Xa and thrombin inhibitors has been found resulting in IC50 values as low as 0.048 μM, a factor of ten more potent than Argatroban. Starting with non-chiral synthetic routes, a new stereospecific route was developed as well as a new solid- phase method.
