1255944-65-0Relevant academic research and scientific papers
A photoinduced Wolff rearrangement/Pd-catalyzed [3+2] cycloaddition sequence: An unexpected route to tetrahydrofurans
Liu, Jie,Li, Miao-Miao,Qu, Bao-Le,Lu, Liang-Qiu,Xiao, Wen-Jing
, p. 2031 - 2034 (2019)
A novel sequential reaction that combines a visible light-induced Wolff rearrangement of α-diazoketones and a Pd-catalyzed [3+2] cycloaddition of vinyl cyclopropanes with the resulting ketenes is described in this work. Selective O-allylic alkylation was observed over C-allylic alkylation, which unexpectedly led to a series of highly functionalized tetrahydrofurans with high efficiency (20 examples, 58-99% yields).
