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CAS

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1256152-35-8

FIIN-1, also known as Fibroblast Growth Factor Receptor (FGFR) Irreversible Inhibitor 1, is a compound that targets and inhibits the fibroblast growth factor receptor tyrosine kinases. These receptors play a significant role in various cellular processes, including cell growth, differentiation, and migration. FIIN-1 is a potent and irreversible inhibitor that can be used to study FGFR-dependent cellular phenomena and may contribute to the development of therapeutically relevant inhibitors for cancer treatment.

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  • 1256152-35-8 Structure

  • Basic information

    1. Product Name: FIIN-1
    2. Synonyms: FIIN-1;FIIN 1 hydrochloride
    3. CAS NO:1256152-35-8
    4. Molecular Formula: C32H39Cl2N7O4
    5. Molecular Weight: 656.60256
    6. EINECS: N/A
    7. Product Categories: Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Tyrosine Kinase Inhibitors;Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors
    8. Mol File: 1256152-35-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: FIIN-1(CAS DataBase Reference)
    10. NIST Chemistry Reference: FIIN-1(1256152-35-8)
    11. EPA Substance Registry System: FIIN-1(1256152-35-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1256152-35-8(Hazardous Substances Data)

1256152-35-8 Usage

Uses

Used in Pharmaceutical Industry:
FIIN-1 is used as a therapeutic agent for targeting fibroblast growth factor receptor tyrosine kinases, which are promising therapeutic targets in a number of cancers. It is particularly useful for wild-type and drug-resistant forms of FGFR kinases, as it can help in the development of irreversible inhibitors that can effectively combat these cancer types.
Used in Cancer Research:
FIIN-1 is used as a research tool to study FGFR-dependent cellular phenomena, which can provide valuable insights into the underlying mechanisms of cancer development and progression. This knowledge can be applied to the development of novel therapeutic strategies and the identification of potential drug targets for cancer treatment.
Used in Drug Development:
FIIN-1 is used as a probe in the development of therapeutically relevant irreversible inhibitors for cancer treatment. By understanding the interactions between FIIN-1 and FGFR kinases, researchers can design more effective and targeted drugs that can overcome drug resistance and improve treatment outcomes for patients with various types of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 1256152-35-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,1,5 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1256152-35:
(9*1)+(8*2)+(7*5)+(6*6)+(5*1)+(4*5)+(3*2)+(2*3)+(1*5)=138
138 % 10 = 8
So 1256152-35-8 is a valid CAS Registry Number.

1256152-35-8Upstream product

1256152-35-8Downstream Products

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