1256161-30-4Relevant academic research and scientific papers
Tandem nucleophilic addition-intramolecular aza-michael reaction: Facile synthesis of chiral fluorinated isoindolines
Fustero, Santos,Moscardo, Javier,Sanchez-Rosello, Maria,Rodriguez, Elsa,Barrio, Pablo
supporting information; experimental part, p. 5494 - 5497 (2011/02/23)
A highly stereoselective synthesis of fluorinated 1,3-disubstituted isoindolines is described. To this end, a tandem reaction consisting of a diastereoselective addition of fluorinated nucleophiles to Ellman's N-(tert-butanesulfinyl)imines followed by an
