1256162-61-4

Basic information

• Product Name: C₂₆H₃₄N₄O₅S
• Synonyms: C₂₆H₃₄N₄O₅S
• CAS NO: 1256162-61-4
• Molecular Weight: 514.646
• Mol File: 1256162-61-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₄N₄O₅S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₄N₄O₅S(1256162-61-4)
• EPA Substance Registry System: C₂₆H₃₄N₄O₅S(1256162-61-4)

Safety Data

• Hazardous Substances Data: 1256162-61-4(Hazardous Substances Data)

Upstream product

• 1201518-34-4 (R)-2-[(4-methobenzyloxyformylamino)methyl]hexanoic acid 
• 1201518-32-2 (R)-2-((4-methoxybenzyloxyamino)methyl)hexanoic acid 
• 1201518-30-0 (S)-3-((R)-2-((4-methoxybenzyloxyamino)methyl)hexanoyl)-4-benzyloxazolidin-2-one 
• 478912-40-2 (4S)-3-(2-methylene-1-oxohexyl)-4-(phenylmethyl)-2-oxazolidinone 
• 4380-88-5 2-butylacrylic acid 
• 534-59-8 n-butylmalonic acid 
• 1256162-57-8 C₂₂H₃₀N₂O₆ 
• 133-08-4 diethyl butylmalonate 
• 7305-71-7 5-methyl-2-thiazol-2-amine 
• 84348-40-3 methyl 4-methylene-L-proline 
• 84348-39-0 (S)-1-tert-butyl 2-methyl 4-methylenepyrrolidine-1,2-dicarboxylate 
• 1256162-56-7 C₂₃H₃₂N₂O₆ 

Relevant articles and documents

Synthesis, antibacterial activity, and biological evaluation of formyl hydroxyamino derivatives as novel potent peptide deformylase inhibitors against drug-resistant bacteria

Peptide deformylase (PDF) has been identified as a promising target for novel antibacterial agents. In this study, a series of novel formyl hydroxyamino derivatives were designed and synthesized as PDF inhibitors and their antibacterial activities were evaluated. Among the potent PDF inhibitors (1o, 1q, 1o′, 1q′, and 1x), in vivo studies showed that compound 1q possesses mild toxicity, a good pharmacokinetic profile and protective effects. The good in vivo efficacy and low toxicity suggest that this class of compounds has potential for development and use in future antibacterial drugs.