1256254-52-0Relevant academic research and scientific papers
Minimizing the contribution of enterohepatic recirculation to clearance in rat for the NCINI class of inhibitors of HIV
Fader, Lee D.,Carson, Rebekah,Morin, Sébastien,Bilodeau, Fran?ois,Chabot, Catherine,Halmos, Ted,Bailey, Murray D.,Kawai, Stephen H.,Coulombe, René,Laplante, Steven,Mekhssian, Kevork,Jakalian, Araz,Garneau, Michel,Duan, Jianmin,Mason, Stephen W.,Simoneau, Bruno,Fenwick, Craig,Tsantrizos, Youla,Yoakim, Christiane
, p. 711 - 716 (2014/07/07)
A scaffold replacement approach was used to identifying the pyridine series of noncatalytic site integrase inhibitors. These molecules bind with higher affinity to a tetrameric form compared to a dimeric form of integrase. Optimization of the C6 and C4 po
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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, (2010/12/01)
Compounds of formula I wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
