1256337-01-5

Upstream product

• 39856-50-3 5-bromo2-nitropyridine 
• 1333509-17-3 1-(tert-butyl) 3-ethyl 2-(6-nitropyridin-3-yl)malonate 
• 415912-99-1 ethyl 2-(6-nitropyridin-3-yl)acetate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1174229-72-1 ethyl 2-(6-aminopyridin-3-yl)acetate 
• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 
• 39891-09-3 (6-chloro-pyridin-3-yl)-acetonitrile 
• 4248-19-5 tert-butyl carbazate 
• 197376-47-9 ethyl (6-chloro-pyridin-3-yl)acetate 

Downstream Products

• 1256337-02-6 (6-tert-butoxycarbonylaminopyridin-3-yl) acetic acid 
• 1260897-34-4 tert-butyl (5-(2-hydroxyethyl)pyridin-2-yl)carbamate 

Relevant academic research and scientific papers

QUINOLONE DERIVATIVES AS FIBROBLAST GROWTH FACTOR INHIBITORS

Compounds of formula (Ι') that are Fibroblast Growth Factor Inhibitors (FGFR) and are therefore useful for the treatment of diseases treatable by inhibition of FGFR are disclosed. Also disclosed are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

BETA-LACTAMASE INHIBITORS

Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.