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5-Methoxycarbonylindole-2-boronic acid pinacol ester is a chemical compound characterized by the molecular formula C16H20BNO4. It is a versatile reagent in organic synthesis, particularly for the formation of carbon-carbon and carbon-heteroatom bonds. 5-Methoxycarbonylindole-2-boronic acid pinacol ester is distinguished by its boronic acid functionality, which is pivotal in the synthesis of a diverse array of biologically active compounds. The pinacol ester group further enhances its stability and ease of handling in various organic reactions, making it a valuable intermediate in medicinal chemistry for the development of pharmaceuticals and other bioactive molecules.

1256358-96-9

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1256358-96-9 Usage

Uses

Used in Organic Synthesis:
5-Methoxycarbonylindole-2-boronic acid pinacol ester is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, facilitating the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-Methoxycarbonylindole-2-boronic acid pinacol ester is used as a building block for the synthesis of various pharmaceuticals and biologically active molecules. Its boronic acid moiety plays a crucial role in the creation of a wide range of biologically active compounds, contributing to the development of new drugs and therapeutic agents.
Used in Drug Development:
5-Methoxycarbonylindole-2-boronic acid pinacol ester is also studied for its potential use in the development of new drugs and therapeutic agents, owing to its unique structural features and reactivity in organic synthesis processes. Its pinacol ester group provides additional stability, which is beneficial for the synthesis and application of these potential therapeutics.

Check Digit Verification of cas no

The CAS Registry Mumber 1256358-96-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,3,5 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1256358-96:
(9*1)+(8*2)+(7*5)+(6*6)+(5*3)+(4*5)+(3*8)+(2*9)+(1*6)=179
179 % 10 = 9
So 1256358-96-9 is a valid CAS Registry Number.

1256358-96-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Methoxycarbonylindole-2-boronic acid pinacol ester

1.2 Other means of identification

Product number -
Other names methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-5-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1256358-96-9 SDS

1256358-96-9Downstream Products

1256358-96-9Relevant academic research and scientific papers

Iridium(I)-Catalyzed C?H Borylation in Air by Using Mechanochemistry

Pang, Yadong,Ishiyama, Tatsuo,Kubota, Koji,Ito, Hajime

, p. 4654 - 4659 (2019)

Mechanochemistry has been applied for the first time to an iridium(I)-catalyzed C?H borylation reaction. By using either none or just a catalytic amount of a liquid, the mechanochemical C?H borylation of a series of heteroaromatic compounds proceeded in air to afford the corresponding arylboronates in good-to-excellent yields. A one-pot mechanochemical C?H borylation/Suzuki–Miyaura cross-coupling sequence for the direct synthesis of 2-aryl indole derivatives is also described. The present study constitutes an important milestone towards the development of industrially attractive solvent-free C?H bond functionalization processes in air.

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