1256360-26-5

Basic information

• Product Name: N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
• Synonyms: 3-Acetamido-4-methoxyphenylboronic acid, pinacol ester;N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide
• CAS NO: 1256360-26-5
• Molecular Formula: C₁₅H₂₂BNO₄
• Molecular Weight: 291.15048
• Mol File: 1256360-26-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 434.4±35.0 °C(Predicted)
• Appearance: /
• Density: 1.10±0.1 g/cm3(Predicted)
• Storage Temp.: Room temperature.
• PKA: 14.60±0.70(Predicted)
• CAS DataBase Reference: N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide(1256360-26-5)
• EPA Substance Registry System: N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide(1256360-26-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 1256360-26-5(Hazardous Substances Data)

Usage

General Description

N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide is a chemical compound with the molecular formula C16H23BO4NO2. It is a boronic acid derivative and has a bulky boron group attached to a phenyl ring. N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide is commonly used in organic synthesis and medicinal chemistry, particularly as a reagent for forming carbon-carbon and carbon-heteroatom bonds. It has also been studied for its potential pharmacological properties, including as an anti-inflammatory and anti-cancer agent. Additionally, its boronic acid functionality allows for selective complexation with certain biological substrates. Overall, N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide is a versatile and important compound in the fields of chemistry and pharmaceuticals.

Upstream product

• 107986-49-2 N-(5-bromo-2-hydroxyphenyl)acetamide 
• 88301-40-0 N-(5-bromo-2-methoxyphenyl)acetamide 
• 73183-34-3 bis(pinacol)diborane 
• 40925-68-6 2-amino-4-bromo-phenol 

Relevant articles and documents

1,2,4-TRIAZINE-4-AMINE DERIVATIVES

According to the invention there is provided a compound of formula A1 which may be useful in the treatment of a condition or disorder ameliorated by the inhibition of the A1- A2b or, particularly, the A2a receptor wherein the compound of formula A1 has the structure, wherein, A represents Cy1 or HetA; Cy1 represents a 5- to 14-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one, two or three rings, which Cy1 group is optionally substituted by one or more R4a substituents; HetA represents a 5- to 14-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one, two or three rings and which HetA group is optionally substituted by one or more R4b substituents; B represents a Cy2 or HetB; Cy2 represents a 3- to 10-membered aromatic, fully saturated or partially unsaturated carbocyclic ring system comprising one or two rings, which Cy2 group is optionally substituted by one or more R4c substituents; HetB represents a 3- to 10-membered heterocyclic group that may be aromatic, fully saturated or partially unsaturated, and which contains one or more heteroatoms selected from O, S and N, which heterocyclic group may comprise one or two rings and which HetB group is optionally substituted by one or more R4d substituents.