125641-44-3Relevant academic research and scientific papers
Synthesis of oxazolidinones and 1,2-diamines from N-alkyl aziridines
Hancock, Matthew T.,Pinhas, Allan R.
, p. 2347 - 2355 (2007/10/03)
Reactions of N-alkyl-substituted aziridines with Lil followed by an electrophile are discussed. In the first series of reactions, the electrophile is carbon dioxide and the product is an oxazolidinone. In all cases, either no reaction occurred or a high y
The conversion of an aziridine plus an iminium salt to a 1,2-diamine
Hancock, Matthew T.,Pinhas, Allan R.
, p. 7125 - 7128 (2007/10/03)
The conversion of an aziridine to a 1,2-diamine using lithium iodide and an iminium salt is discussed. We have found that when the aziridine is substituted by only alkyl groups, it is the less substituted carbon-nitrogen bond that is broken; whereas, when the aziridine is substituted by a phenyl group at either the nitrogen or the carbon, it is the more substituted carbon-nitrogen bond that is broken. For a 2,3-disubstituted aziridine, the reaction sequence goes with net retention of stereochemistry.
A Novel Synthesis of Unsymmetric 1,2-Diamines from N-Substituted 2-Methylaziridines
Chamchaang, Wilaiporn,Pinhas, Allan R.
, p. 2531 - 2533 (2007/10/02)
This paper reports a one-pot synthesis of unsymmetric 1,2-diamines from aziridines and amine oxide, using lithium iodide and triiron dodecacarbonyl in THF.
