24417-03-6Relevant academic research and scientific papers
Achieving regio- and stereo-control in the fluorination of aziridines under acidic conditions
Okoromoba, Otome E.,Li, Zhou,Robertson, Nicole,Mashuta, Mark S.,Couto, Uenifer R.,Tormena, Cláudio F.,Xu, Bo,Hammond, Gerald B.
supporting information, p. 13353 - 13356 (2016/11/18)
We developed an efficient fluorination protocol that converts easily accessible aziridines into β-fluoroamines, which are important motifs in biologically active molecules. In contrast with traditional fluorination approaches, DMPU-HF has shown both highe
New phenylselanyl group activation: Synthesis of aziridines and oxazolidin-2-ones
Miniejew, Catherine,Outurquin, Francis,Pannecoucke, Xavier
, p. 1575 - 1576 (2007/10/03)
After the study of different phenylselanyl group activators, halogenation by N-bromosuccinimide (NBS) has been shown to be the most suitable manner for cyclizing β-phenylselanyl amines into aziridines and also enabled production of oxazolidin-2-ones from N-Boc β-phenylselanyl amines in excellent yield.
Stereospecific synthesis of 2,3-disubstituted aziridines from β- alkylamino phenylselenides
Boivin, Stéphane,Outurquin, Francis,Paulmier, Claude
, p. 663 - 666 (2007/10/03)
Reduction of α-phenylselanyl imines derived from β-phenylselanyl α- oxoesters or PhSeCl assisted nucleophilic addition of primary amines to α,β-unsaturated esters have led to β-alkylamino phenylselenides 4, 5, 12 and 13 which were cyclised into aziridines
The Conversion of an Aziridine to a β-Lactam
Chamchaang, Wilaiporn,Pinhas, Allan R.
, p. 2943 - 2950 (2007/10/02)
A one-pot, inert atmosphere conversion of an aziridine to a β-lactam using nickel tetracarbonyl as the carbonyl source is described.In this reaction it is the less substituted carbon-nitrogen bond which is carbonylated.The proposed mechanism for this reac
A MILD CYCLIZATION OF 2-AMINOALCOHOLS TO AZIRIDINES USING DIPHOSPHORUS TETRAIODIDE
Suzuki, Hitomi,Tani, Hiroyuki
, p. 2129 - 2130 (2007/10/02)
The reaction of 2-aminoalcohols with diphosphorus tetraiodide in benzene at room temperature leads to the corresponding aziridines in good to moderate yields.
REDUCTION DE PHENYLSULFONYL-2 AZIRIDINES. SYNTHESE DE PHENYLTHIO-2 AZIRIDINES
Gaillot, Jean-Marc,Gelas-Mialhe, Yvonne,Vessiere, Roger
, p. 1137 - 1140 (2007/10/02)
Reductive cleavage of 2-phenylsulfonylaziridines with sodium amalgam provides an attractive synthetic route to 2-unsubstituted aziridines.LiAlH4 gives several compounds.DIBAH causes a sulfur-oxygen cleavage to form 2-phenylthioaziridines which are also prepared from 2-phenylsulfinylaziridines.
