125641-48-7Relevant academic research and scientific papers
The conversion of an aziridine plus an iminium salt to a 1,2-diamine
Hancock, Matthew T.,Pinhas, Allan R.
, p. 7125 - 7128 (2007/10/03)
The conversion of an aziridine to a 1,2-diamine using lithium iodide and an iminium salt is discussed. We have found that when the aziridine is substituted by only alkyl groups, it is the less substituted carbon-nitrogen bond that is broken; whereas, when the aziridine is substituted by a phenyl group at either the nitrogen or the carbon, it is the more substituted carbon-nitrogen bond that is broken. For a 2,3-disubstituted aziridine, the reaction sequence goes with net retention of stereochemistry.
A Novel Synthesis of Unsymmetric 1,2-Diamines from N-Substituted 2-Methylaziridines
Chamchaang, Wilaiporn,Pinhas, Allan R.
, p. 2531 - 2533 (2007/10/02)
This paper reports a one-pot synthesis of unsymmetric 1,2-diamines from aziridines and amine oxide, using lithium iodide and triiron dodecacarbonyl in THF.
