1256836-65-3

Usage

Compound type

pyrazolopyridine derivative

Contains

a trifluoromethyl group

Pharmaceutical applications

studied for potential uses as a building block for the synthesis of biologically active compounds

Other potential uses

in agrochemicals and materials science

Unique properties

the trifluoromethyl group imparts unique chemical and physical properties, making it valuable for various research and industrial applications.

Upstream product

• 117519-09-2 3-amino-2-chloro-6-(trifluoromethyl)pyridine 
• 1383735-00-9 N-(2-methyl-6-(trifluoromethyl)pyridin-3-yl)acetamide 
• 383907-17-3 2-methyl-6-(trifluoromethyl)pyridin-3-amine 

Downstream Products

• 1383735-01-0 C₁₃H₇F₄N₃ 
• 1383735-52-1 1-(4-fluorophenyl)-5-trifluoromethyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine 
• 1383735-56-5 C₁₃H₁₁F₄N₃ 
• 1383735-55-4 C₁₃H₁₁F₄N₃ 

Relevant academic research and scientific papers

UREA, AMIDE, AND SUBSTITUTED HETEROARYL COMPOUNDS FOR CBL-B INHIBITION

Compounds of formulae (I) and (II), compositions, and methods for use in inhibiting the E3 enzyme Cbl-b in the ubiquitin proteasome pathway are disclosed. The compounds, compositions, and methods can be used to modulate the immune system, to treat diseases amenable to immune system modulation, and for treatment of cells invivo, in vitro, or ex vivo.

PYRAZOLOPIPERIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS

Disclosed are compounds of the formula (I), useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of CCR1 including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Also disclosed are methods of making and methods of using same.