1256841-99-2Relevant academic research and scientific papers
Enantioselective desymmetrization of cyclopropenes by hydroacylation
Phan, Diem H. T.,Kou, Kevin G. M.,Dong, Vy M.
supporting information; experimental part, p. 16354 - 16355 (2011/02/24)
We report an enantioselective desymmetrization of cyclopropenes by intermolecular Rh-catalyzed hydroacylation. Cyclopropylketones, bearing quaternary stereocenters, are produced with diastereocontrol (up to >20:1) and excellent enantiomeric excess (up to >99 ee).
