125686-19-3

Upstream product

• 95694-42-1 2-Diazo-1,3-bis(2,4,6-trimethylphenyl)-1,3-propandion 
• 109-73-9 N-butylamine 

Relevant academic research and scientific papers

(E)- and (Z)-Enols of β-Ketocarboxylic Acid Amides

Reaction of dimesitoyldiazomethane (1) with ammonia (3a), primary and secondary amines (3b-o and 3p-v, respectively) leads to the completely enolized amides 4a-v.Besides the chelated Z configuration the unusual E isomer exists in the most cases, too.The Z/E distribution in the equilibrium depends on the steric and electronic effects present in the amide group CONR2R3 and on the solvent.