1256929-79-9Relevant academic research and scientific papers
New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes
El-Sagheer, Afaf H.,Brown, Tom
scheme or table, p. 15329 - 15334 (2011/02/24)
The CuAAC reaction (click chemistry) has been used in conjunction with solid-phase synthesis to produce catalytically active hairpin ribozymes around 100 nucleotides in length. Cross-strand ligation through neighboring nucleobases was successful in covale
