1256930-33-2Relevant academic research and scientific papers
Sequential double α-arylation of N -allylureas by asymmetric deprotonation and N→C aryl migration
Tetlow, Daniel J.,Hennecke, Ulrich,Raftery, James,Waring, Michael J.,Clarke, David S.,Clayden, Jonathan
supporting information; experimental part, p. 5442 - 5445 (2011/02/22)
On lithiation with lithium amides, N-allyl-N'-aryl ureas undergo rearrangement with transfer of the aryl ring from N to the allylic α carbon. From the α-arylated products, a further aryl transfer under the influence of a chiral lithium amide allows the en
