125697-99-6Relevant academic research and scientific papers
Inhibition of 5-lipoxygenase by substituted 3,4-dihydro-2H-1,4-thiazines
Weintraub,Skoog,Nichols,Wiseman,Huber,Baugh,Farrell
, p. 937 - 943 (1989)
A series of substituted 3,4-dihydro-2H-1,4-thiazines inhibit 5-lipoxygenase from rat leukocytes and exhibit submicromolar IC50 values. A novel synthesis of these compounds was developed based on the formation of hydroxymethyleneamine 13 and its
