1257079-01-8

Basic information

• Product Name: 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-N-(4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)pyrimidin-2-amine
• Synonyms: 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-N-(4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)pyrimidin-2-amine
• CAS NO: 1257079-01-8
• Molecular Weight: 484.025
• Mol File: 1257079-01-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-N-(4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)pyrimidin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-N-(4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)pyrimidin-2-amine(1257079-01-8)
• EPA Substance Registry System: 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-N-(4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)pyrimidin-2-amine(1257079-01-8)

Safety Data

• Hazardous Substances Data: 1257079-01-8(Hazardous Substances Data)

Upstream product

• 23576-81-0 6-chloroimidazo[2,1-b]thiazole 
• 1257078-98-0 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)pyrimidin-2-amine 
• 1257078-99-1 4-(6-chloroimidazo[2,1-b] thiazol-5-yl)pyrimidin-2-ol 
• 1257078-95-7 (E)-1-(6-chloroimidazo[2,1-b]thiazol-5-yl)-3-(dimethylamino)prop-2-en-1-one 
• 1257078-94-6 1-(6-chloroimidazo[2,1-b]thiazol-5-yl)ethanone 
• 448-19-1 4-fluoro-2-methoxy-1-nitrobenzene 
• 50533-97-6 dimethyl-piperidin-4-yl-amine 
• 1089279-91-3 1-(4-amino-3-methoxyphenyl)-N,N-dimethylpiperidine-4-amine 
• 1257079-00-7 6-chloro-5-(2-chloropyrimidin-4-yl)imidazo[2,1-b]thiazole 

Relevant articles and documents

PYRIMIDINE INHIBITORS OF KINASE ACTIVITY

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-IR.