125718-72-1Relevant articles and documents
Chiral bisphosphine ligands based on quinoline oligoamide foldamers: application in asymmetric hydrogenation
Zheng, Lu,Zheng, Dan,Wang, Yanru,Yu, Chengyuan,Zhang, Kun,Jiang, Hua
, p. 9573 - 9577 (2019/11/20)
A series of chiral bisphosphine ligands were designed and synthesized based on single-handed quinoline oligoamide foldamers. The bisphosphine ligands can coordinate with Rh(cod)2BF4 in a 1 : 1 stoichiometry and the resulted chiral Rh(i) catalysts were applied in the asymmetric hydrogenation of α-dehydroamino acid esters, in which excellent conversions and promising levels of enantioselectivity were achieved.
Axial 4,4′,6,6′-tetrakis-trifluoromethyl-biphenyl-2, 2′diamine (TF-BIPHAM): Resolution and applications in asymmetric hydrogenation
Wang, Chun-Jiang,Gao, Feng,Liang, Gang
supporting information; experimental part, p. 4711 - 4714 (2009/05/31)
(Equation Presented) The racemic TF-BIPHAM was resolved for the first time, and the effectiveness of the resolved diamine was demonstrated by highly enantioselective hydrogenation of α-aryl enamides and α-dehydroamino acid esters using readily accessible
Synthesis of (S)-3,4-dihydroxyphenylalanine (L-DOPA) and unnatural α-amino acids via enzymatic resolution using alcalase
Tyagi, O D,Boll, P M,Parmar, V S,Taneja, Poonam,Singh, S K
, p. 851 - 854 (2007/10/02)
Enzymatic resolution has been used for the synthesis of L-DOPA with high optical purity.N-Acetyl-(R,S)-3,4-methylenedioxyphenylalanine methyl ester (2b) on enzymatic resolution by alcalase (Subtilisin Carlsberg) yields N-acetyl-(S)-3,4-methylenedioxyphenylalanine (3b) which upon acid treatment affords (S)-3,4-dihydroxyphenylalanine (L-DOPA) (4).Several optically active unnatural N-acetylated and N-benzoylated α-amino acids have been prepared by similar enzymatic resolution.
Palladium-Catalyzed Synthesis of Didehydroamino Acid Derivatives
Carlstroem, Anne-Sofie,Frejd, Torbjoern
, p. 414 - 418 (2007/10/02)
The palladium-catalyzed coupling of 2-amidoacrylates with aryl iodides under phase-transfer conditions yields aromatic (Z)-didehydroamino acid derivatives, which give various protected aromatic amino acids via catalytic hydrogenation using Pd/C or the Wil