1257387-95-3

Basic information

• Product Name: (3R)-(3,5-difluorophenyl)-12-oxa-1,4-diazadispiro[5.2.5.2]hexadecan-5-one
• Synonyms: (3R)-(3,5-difluorophenyl)-12-oxa-1,4-diazadispiro[5.2.5.2]hexadecan-5-one
• CAS NO: 1257387-95-3
• Molecular Weight: 350.409
• Mol File: 1257387-95-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R)-(3,5-difluorophenyl)-12-oxa-1,4-diazadispiro[5.2.5.2]hexadecan-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R)-(3,5-difluorophenyl)-12-oxa-1,4-diazadispiro[5.2.5.2]hexadecan-5-one(1257387-95-3)
• EPA Substance Registry System: (3R)-(3,5-difluorophenyl)-12-oxa-1,4-diazadispiro[5.2.5.2]hexadecan-5-one(1257387-95-3)

Safety Data

• Hazardous Substances Data: 1257387-95-3(Hazardous Substances Data)

Upstream product

• 50675-18-8 3,4,5,6-tetrahydro-2H-pyran-4-carbaldehyde 
• 1159280-53-1 3-oxaspiro[5.5]undecan-9-one 
• 67-66-3 chloroform 
• 1159280-52-0 9-oxaspiro[5.5]undec-4-en-3-one 

Downstream Products

• 1257387-96-4 tert-butyl (3R)-(3,5-difluorophenyl)-5-oxo-12-oxa-1,4-diaza-dispiro[5.2.5.2]hexadecane-1-carboxylate 
• 1257387-53-3 2-((R)-3-(3,5-difluoro-phenyl)-5-oxo-12-oxa-1,4-diaza-dispiro[5.2.5.2]hexadecan-4-yl)-N-((R)-2'-oxo-1,1',2',3-tetrahydrospiro[inden-2,3'-pyrrolo[2,3-b]pyridin]-5-yl)acetamide 
• 1257387-98-6 tert-butyl (3R)-(3,5-difluorophenyl)-4-methoxycarbonylmethyl-5-oxo-12-oxa-1,4-diaza-dispiro[5.2.5.2]-hexadecane-1-carboxylate 

Relevant articles and documents

NEW 5-ALKYNYL-PYRIDINES

The present invention relates to new CGRP-antagonists of general formula I wherein R1, R2, R3, Ra, Rb, Rc, X, Y and Z are defined as mentioned hereinafter, the individual diastereomers, the individual enantiomers and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, medicaments containing these compounds, the use thereof and processes for the preparation thereof.