125749-65-7Relevant academic research and scientific papers
Stereoselective Synthesis of (Rp)-Benzylphenyl-phosphine Oxide from (S)-(+)-Prolinol by the Michaelis-Arbuzov Reaction: Application in the Synthesis of a Chiral Hybrid Phosphine-Phosphine Oxide Ligand
Faure, Bruno,Archavlis, Albert,Buono, Gerard
, p. 805 - 807 (1989)
The chiral oxazaphospholidine (2) derived from (S)-(+)-prolinol reacts with benzyl bromide in a stereoselective Michaelis-Arbuzov reaction to give (3), an ideal precursor for the synthesis of the chiral hybrid phosphine-phosphine oxide ligand (5).
Reactivity of chiral oxazaphospholidines on activated halide compounds: Synthesis and coordination studies of chiral hybrid phosphine-phosphine oxide ligands
Faure, Bruno,Pardigon, Olivier,Buono, Gerard
, p. 11577 - 11594 (1997)
The Michaelis Arbuzov reaction between the enantiopure 2-phenyl-1,3,2-oxazaphospholidine 1 and different activated halide compounds 2 afforded with total diastereoselectivity chiral phosphinamides 3. Oxazaphospholidine 1 reacted with α-haloacetophenones 4
