1257648-07-9Relevant academic research and scientific papers
1-(5-carboxyindol-1-yl)propan-2-one inhibitors of human cytosolic phospholipase A2α: Effect of substituents in position 3 of the indole scaffold on inhibitory potency, metabolic stability, solubility, and bioavailability
Bovens, Stefanie,Schulze Elfringhoff, Alwine,Kaptur, Martina,Reinhardt, Dirk,Sch?fers, Michael,Lehr, Matthias
supporting information; experimental part, p. 8298 - 8308 (2011/02/23)
Indole-5-carboxylic acids with 3-aryloxy-2-oxopropyl residues in position 1 have been found to be potent inhibitors of human cytosolic phospholipase A 2α (cPLA2α). In the course of structure-activity relationship studies, we investig
