125774-14-3Relevant academic research and scientific papers
α-tosyloxyketones: Convenient [4+3] cycloaddition precursors
Handy, Scott T.,Okello, Maurice
, p. 489 - 491 (2002)
A concise, simple two-step method for the preparation of [4+3] cycloadducts from ketones using Koser's reagent and trifuoroethanol-triethylamine has been developed. This sequence affords yields similar to those obtained using the α-halo and α-mesyloxyketo
Homogeneous supported synthesis using ionic liquid supports: Tunable separation properties
Handy, Scott T.,Okello, Maurice
, p. 2874 - 2877 (2005)
(Chemical Equation Presented) We report a homogeneous supported version of Koser's salt based on a room-temperature ionic liquid (RTIL) support. By altering the nature of the RTIL, a material was developed that was stable, recyclable, and readily separable from the tosyloxylated ketone products just by using variations in solvent polarity. A similar approach should be applicable to a wide range of supported catalysts and reagents.
Oxy-Allyl Cation Catalysis: An Enantioselective Electrophilic Activation Mode
Liu, Chun,Oblak, E. Zachary,Vander Wal, Mark N.,Dilger, Andrew K.,Almstead, Danielle K.,MacMillan, David W.C.
supporting information, p. 2134 - 2137 (2016/03/05)
A generic activation mode for asymmetric LUMO-lowering catalysis has been developed using the long-established principles of oxy-allyl cation chemistry. Here, the enantioselective conversion of racemic α-tosyloxy ketones to optically enriched α-indolic ca
2,4,6-Tris(4-iodophenoxy)-1,3,5-triazine as a new recyclable "iodoarene" for in situ generation of hypervalent iodine(III) reagent for α-tosyloxylation of enolizable ketones
Thorat, Prerana B.,Bhong, Bhagyashree Y.,Shelke, Amol V.,Karade, Nandkishor N.
, p. 3332 - 3335 (2014/06/09)
The synthesis of 2,4,6-tris[(4-iodo)phenoxy)]-1,3,5-triazine 6, as a new recyclable nonpolymeric analogue of iodobenzene is achieved using the reaction of 2,4,6-trichloro-1,3,5-triazine with 4-iodophenol in the presence of KOH. The application of 6 as a r
Synthesis of α,ω-dicarboxylic acid dimethyl esters from cycloalkanones
Lee, Jong Chan,Ku, Chang Hoe
, p. 1679 - 1680 (2007/10/03)
Reaction of cycloalkanones with [hydroxy(2,4-dinitrobenzenesulfonyloxy)iodo]benzene and subsequent treatment of α-[(2,4-dinitrobenzene)sulfonyl]oxy cycloalkanone intermediates with Oxone and PTSA in MeOH-H2O (6:1, v/v) solution provided dicarboxylic acid dimethyl esters in high yields.
Ultrasound Promoted Hypervalent Iodine Reactions: α-Tosyloxylation of Ketones with Benzene
Tuncay, Atilla,Dustman, John A.,Fisher, George,Tuncay, Crystal I.,Suslick, Kenneth S.
, p. 7647 - 7650 (2007/10/02)
Ultrasound enhances substantially the rats of α-tosyloxylation of ketones with benzene and thus provides a direct, quick, and mild method of tosyloxylation of ketones without the generation of timeconsuming intermediates such as tri
