125782-57-2Relevant academic research and scientific papers
Synthesis, conformation, and immunosuppressive activity of cyclosporines that contain ε-oxygen (4R)-4-[(E)-butenyl]-4,N-dimethyl-L-threonine analogues in the 1-position
Sun,Guillaume,Dunlap,Rich
, p. 1443 - 1452 (2007/10/02)
A series of CsA analogues that contain novel ε-oxygen isosteres of (4R)-4-[(E)-butenyl]-4,N-dimethyl-L-threonine (MeBmt) in the 1-position were synthesized. The key steps for the syntheses of enantiomerically pure ε-oxygen MeBmt analogues 4-7 were based o
