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1257864-49-5

N,N'-bis(4-(4-methylpiperazin-1-yl)butylamino)-2,6-bis(4-(4-methylpiperazin-1-yl)butylamino)-1,2,5,8-naphthalenetetracarboxylic acid diimide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • N,N'-bis(4-(4-methylpiperazin-1-yl)butylamino)-2,6-bis(4-(4-methylpiperazin-1-yl)butylamino)-1,2,5,8-naphthalenetetracarboxylic acid diimide

    Cas No: 1257864-49-5

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  • 1257864-49-5 Structure

  • Basic information

    1. Product Name: N,N'-bis(4-(4-methylpiperazin-1-yl)butylamino)-2,6-bis(4-(4-methylpiperazin-1-yl)butylamino)-1,2,5,8-naphthalenetetracarboxylic acid diimide
    2. Synonyms: N,N'-bis(4-(4-methylpiperazin-1-yl)butylamino)-2,6-bis(4-(4-methylpiperazin-1-yl)butylamino)-1,2,5,8-naphthalenetetracarboxylic acid diimide
    3. CAS NO:1257864-49-5
    4. Molecular Formula:
    5. Molecular Weight: 913.263
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1257864-49-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N,N'-bis(4-(4-methylpiperazin-1-yl)butylamino)-2,6-bis(4-(4-methylpiperazin-1-yl)butylamino)-1,2,5,8-naphthalenetetracarboxylic acid diimide(CAS DataBase Reference)
    10. NIST Chemistry Reference: N,N'-bis(4-(4-methylpiperazin-1-yl)butylamino)-2,6-bis(4-(4-methylpiperazin-1-yl)butylamino)-1,2,5,8-naphthalenetetracarboxylic acid diimide(1257864-49-5)
    11. EPA Substance Registry System: N,N'-bis(4-(4-methylpiperazin-1-yl)butylamino)-2,6-bis(4-(4-methylpiperazin-1-yl)butylamino)-1,2,5,8-naphthalenetetracarboxylic acid diimide(1257864-49-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1257864-49-5(Hazardous Substances Data)

1257864-49-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1257864-49-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,7,8,6 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1257864-49:
(9*1)+(8*2)+(7*5)+(6*7)+(5*8)+(4*6)+(3*4)+(2*4)+(1*9)=195
195 % 10 = 5
So 1257864-49-5 is a valid CAS Registry Number.

1257864-49-5Downstream Products

1257864-49-5Relevant articles and documents

Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells

Hampel, Sonja M.,Sidibe, Assitan,Gunaratnam, Mekala,Riou, Jean-Franois,Neidle, Stephen

supporting information; experimental part, p. 6459 - 6463 (2010/12/18)

A series of tetrasubstituted naphthalene diimide compounds with N-methylpiperazine end groups has been synthesized and evaluated as G-quadruplex ligands. They have high affinity and selectivity for telomeric G-quadruplex DNA over duplex DNA. CD studies show that they induce formation of a parallel G-quadruplex topology. They inhibit the binding of hPOT1 and topoisomerase IIIα to telomeric DNA and inhibit telomerase activity in MCF7 cells. The compounds have potent activity in a panel of cancer cell lines, with typical IC50 values of ～0.1 μM, and up to 100-fold lower toxicity in a normal human fibroblast cell line.

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