1257875-02-7

Basic information

• Product Name: C₂₃H₃₁N₂O₂PS
• Synonyms: C₂₃H₃₁N₂O₂PS
• CAS NO: 1257875-02-7
• Molecular Weight: 430.551
• Mol File: 1257875-02-7.mol

Chemical Properties

• CAS DataBase Reference: C₂₃H₃₁N₂O₂PS(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₃₁N₂O₂PS(1257875-02-7)
• EPA Substance Registry System: C₂₃H₃₁N₂O₂PS(1257875-02-7)

Safety Data

• Hazardous Substances Data: 1257875-02-7(Hazardous Substances Data)

Upstream product

• 1015-37-8 diphenylthiophosphinoyl chloride 
• 146504-07-6 tert-butyl ((1R,2R)-2-aminocyclohexyl)carbamate 

Downstream Products

• 643009-78-3 (1R,2R)-(-)-N-diphenylthiophosphorylcyclohexane-1,2-diamine 

Relevant articles and documents

Highly enantioselective michael addition of acetone to nitro olefins catalyzed by chiral bifunctional primary amine-thiophosphoramide catalyst

A series of bifunctional primary amine-thiophosphoramides were synthesized, which proven to be effective organocatalysts for the asymmetric Michael reaction of acetone to both aryl and alkyl nitro olefins in the presence of phenol as a protic additive. The corresponding adducts were obtained in excellent chemical yields (up to >99%) with excellent enantioselectivities (up to 97% ee). A novel chiral phosphoramide functions well as an efficient bifunctional organocatalyst for the asymmetric Michael addition of acetone, one of the most challenge substrate in Michael addition, to nitro olefinsto afford the corresponding syntheticvaluable γ-nitro ketones in good to excellent yield with high levels of enantioselectivities (up to 97% ee, respectively).