1258000-11-1

Basic information

• Product Name: C₂₁H₂₄F₂N₂
• Synonyms: C₂₁H₂₄F₂N₂
• CAS NO: 1258000-11-1
• Molecular Weight: 342.432
• Mol File: 1258000-11-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₄F₂N₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₄F₂N₂(1258000-11-1)
• EPA Substance Registry System: C₂₁H₂₄F₂N₂(1258000-11-1)

Safety Data

• Hazardous Substances Data: 1258000-11-1(Hazardous Substances Data)

Upstream product

• 1258000-10-0 C₂₆H₃₂F₂N₂O₂ 

Downstream Products

• 1257999-92-0 C₂₈H₂₇ClF₂N₂O 

Relevant articles and documents

Design, syntheses, and SAR of 2,8-diazaspiro[4.5]decanones as T-type calcium channel antagonists

It was hypothesized that an appropriately substituted 2,8-diazaspiro[4.5] decan-1-one could effectively approximate a 5-feature T-type pharmacophore model published in the literature. Compounds were designed and synthesized to test our hypothesis and were found to be potent T-type calcium channel inhibitors with modest selectivity over L-type calcium channels. The synthesis and SAR of the series is described.