1258153-63-7Relevant academic research and scientific papers
Synthesis of ACAT inhibitors through substitution using allylic picolinate and copper reagent
Kobayashi, Yuichi,Lalitnorasate, Paveena,Kaneko, Yuki,Kiyotsuka, Yohei,Endo, Yoshiki
, p. 6018 - 6021 (2010)
Amide of an octanoic acid possessing an aryl group at C3 position is a highly potent ACAT inhibitor. In this paper, we describe a synthetic access to this class of compounds as optically active forms. The key reaction is substitution of the allylic picoli
