1258282-48-2

Upstream product

• 1258282-47-1 1-(2-chloro-5-nitrophenyl)isoquinoline 
• 7568-93-6 2-Amino-1-phenylethanol 
• 25784-91-2 2-chloro-5-nitrobenzoylchloride 
• 1258282-46-0 2-chloro-N-(2-hydroxy-2-phenylethyl)-5-nitrobenzamide 

Downstream Products

• 1258282-39-1 C₂₃H₁₆Cl₂N₂O₃S 
• 1258282-40-4 C₂₂H₁₆ClN₃O 
• 1258282-42-6 C₂₁H₁₃Cl₂N₃O₄S 
• 1609355-17-0 C₂₅H₂₀ClN₃O₃S 
• 1609355-48-7 N-(4-chloro-3-(isoquinolin-1-yl)phenyl)-4-(3,3-dioxido-1,3,4-oxathiazinan-4-yl)-2-fluorobenzamide 
• 1609355-45-4 C₂₅H₁₉Cl₂N₃O₃S 
• 1609355-22-7 C₂₅H₁₉ClFN₃O₃S 
• 1609355-39-6 N-(4-chloro-3-(isoquinolin-1-yl)phenyl)-4-(3,3-dioxido-1,3,4-oxathiazinan-4-yl)benzamide 
• 1609355-35-2 2-chloro-N-(4-chloro-3-(isoquinolin-1-yl)phenyl)-4-(3,3-dioxido-1,3,4-oxathiazinan-4-yl)benzamide 
• 1609355-46-5 C₂₆H₂₁Cl₂N₃O₃S 

Relevant academic research and scientific papers

CYCLIC SULFONAMIDE CONTAINING DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING PATHWAY

The invention relates generally to the creation and use of cyclic sulfonamide containing derivatives to inhibit the hedgehog signaling pathway and to the use of those compounds for the treatment of hyperproliferative diseases and angiogenesis mediated diseases.

ISOQUINOLINE, QUINOLINE, AND QUINAZOLINE DERIVATIVES AS INHIBITORS OF HEDGEHOG SIGNALING

The invention provides isoquinoline, quinoline, and quinazoline derivatives to treat a variety of disorders, diseases and pathologic conditions, and more specifically to the use of isoquinoline, quinoline, and quinazoline derivatives to inhibit the hedgehog signaling pathway and to the use of those compounds to the treatment of hyperproliferative diseases and pathologic angiogenesis.