1258328-73-2

Basic information

• Product Name: diethyl 2-(cyclohexylamino)-5-{cyclohexyl[(8-methoxy-2-oxo-2H-chromen-3-yl)carbonyl]amino}-3,4-furandicarboxylate
• Synonyms: diethyl 2-(cyclohexylamino)-5-{cyclohexyl[(8-methoxy-2-oxo-2H-chromen-3-yl)carbonyl]amino}-3,4-furandicarboxylate
• CAS NO: 1258328-73-2
• Molecular Weight: 608.689
• Mol File: 1258328-73-2.mol

Chemical Properties

• CAS DataBase Reference: diethyl 2-(cyclohexylamino)-5-{cyclohexyl[(8-methoxy-2-oxo-2H-chromen-3-yl)carbonyl]amino}-3,4-furandicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 2-(cyclohexylamino)-5-{cyclohexyl[(8-methoxy-2-oxo-2H-chromen-3-yl)carbonyl]amino}-3,4-furandicarboxylate(1258328-73-2)
• EPA Substance Registry System: diethyl 2-(cyclohexylamino)-5-{cyclohexyl[(8-methoxy-2-oxo-2H-chromen-3-yl)carbonyl]amino}-3,4-furandicarboxylate(1258328-73-2)

Safety Data

• Hazardous Substances Data: 1258328-73-2(Hazardous Substances Data)

Upstream product

• 931-53-3 Cyclohexyl isocyanide 
• 2555-20-6 8-methoxy-2-oxo-2H-chromene-3-carboxylic acid 
• 762-21-0 acetylenedicarboxylic acid diethyl ester 

Relevant articles and documents

Synthesis of 2-(alkylamino)-5-{alkyl[(2-oxo-2H-chromen-3-yl)carbonyl]amino} -3,4-furandicarboxylates using a multi-component reaction in water

A simple synthesis of 2-(alkylamino)-5-{alkyl[(2-oxo-2H-chromen-3-yl) carbonyl]amino}-3,4-furandicarboxylates via a one-pot multi-component reaction is described. The reactive 1:1 zwitterionic intermediate generated from the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped at room temperature by coumarin-3-carboxylic acids prepared in situ from a 2-hydroxy aromatic aldehyde and Meldrum's acid to afford the title compounds in good to excellent yields.