1258594-97-6

Basic information

• Product Name: diethyl 3-(2-(2-(4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenoxy)ethoxy)ethoxy)-1,1-difluoropropylphosphonate
• Synonyms: diethyl 3-(2-(2-(4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenoxy)ethoxy)ethoxy)-1,1-difluoropropylphosphonate
• CAS NO: 1258594-97-6
• Molecular Weight: 645.684
• Mol File: 1258594-97-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: diethyl 3-(2-(2-(4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenoxy)ethoxy)ethoxy)-1,1-difluoropropylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 3-(2-(2-(4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenoxy)ethoxy)ethoxy)-1,1-difluoropropylphosphonate(1258594-97-6)
• EPA Substance Registry System: diethyl 3-(2-(2-(4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenoxy)ethoxy)ethoxy)-1,1-difluoropropylphosphonate(1258594-97-6)

Safety Data

• Hazardous Substances Data: 1258594-97-6(Hazardous Substances Data)

Upstream product

• 36839-55-1 1,2-bis-(2-iodoethoxy)ethane 
• 1478-53-1 Diethyl difluoromethylphosphonate 
• 74331-69-4 1-ethynyl-4-methoxy-2-methylbenzene 
• 1150561-75-3 tert-butyl 5-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylcarbamate 
• 1186637-29-5 tert-butyl (2-bromo-5-methylphenyl)carbamate 
• 1186635-51-7 4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenol 
• 1258594-96-5 diethyl 1,1-difluoro-3-(2-(2-iodoethoxy)ethoxy)propylphosphonate 
• 1186635-50-6 2-(4-methoxy-2-methylphenethyl)-8-methylbenzo[f][1,7]naphthyridin-5-amine 
• 1186637-70-6 2-((4-methoxy-2-methylphenyl)ethynyl)-8-methylbenzo[f][1,7]naphthyridin-5-amine 
• 1186637-69-3 3-chloro-5-((4-methoxy-2-methylphenyl)ethynyl)picolinonitrile 
• 85331-33-5 2-Cyano-3,5-dichloropyridine 
• 53078-85-6 2-bromo-5-methylaniline 

Downstream Products

• 1258594-95-4 (3-(2-(2-(4-(2-(5-amino-8-methylbenzo[f][1,7]naphthyridin-2-yl)ethyl)-3-methylphenoxy)ethoxy)ethoxy)-1,1-difluoropropyl)phosphonic acid 

Relevant articles and documents

Compounds and compositions as TLR activity modulators

The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.

COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS

The invention provides a novel class of compounds, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 7. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine.