1258709-95-3Relevant academic research and scientific papers
BACE1 inhibitory activities of enantiomerically pure, variously substituted N-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl) arylsulfonamides
Bertini, Simone,Ghilardi, Elisa,Asso, Valentina,Granchi, Carlotta,Minutolo, Filippo,Pineschi, Mauro,Di Bussolo, Valeria,Bortolato, Andrea,Moro, Stefano,Saba, Alessandro,MacChia, Marco
, p. 7991 - 7996 (2010)
β-Secretase (BACE1) has been widely recognized as one of the possible therapeutic targets for the treatment of Alzheimer's disease. In this paper, we report the synthesis and the BACE1 inhibitory activity of new, variously substituted N-(3-(4-benzhydrylpi
