125889-28-3Relevant academic research and scientific papers
Metalation of arylmethyl alkyl ethers
Azzena, Ugo,Pilo, Luciano,Sechi, Alessandra
, p. 12389 - 12398 (2007/10/03)
Arylmethyl alkyl ethers 1a-11 were metallated with n-BuLi or sec-BuLi in THF at different temperatures, affording α-alkoxy-substituted arylmethyllithium derivatives. At low temperature, the organometallics derived from methyl and isopropyl ethers are suff
A NOVEL ORDER OF orto-DIRECTING ABILITIES IN THE LITHIATION OF ε6-ARENETRICARBONYLCHROMIUM(0) COMPLEXES
Gilday, John, P.,Negri, Joanna T.,Widdowson, David A.
, p. 4605 - 4618 (2007/10/02)
A ranking order of ortho-lithiation directed by various functional groups in arenetricarbonylchromium complexes has been determined.This order differs from that found in the free arene series.Inductive effects were found to be the dominant factor for the determination of the site of lithiation.Fluorine was found the most powerful ortho direction of the groups studied.Additionally, fluorine was found to be a strong ortho director in the uncomplexed series under kinetic conditions.
