1258934-71-2

Upstream product

• 766-98-3 1-ethynyl-4-fluorobenzene 
• 1258934-68-7 tert-butyl N-(5-iodo-1,3-thiazol-4-yl)carbamate 
• 1235406-42-4 thiazol-4-ylaminocarboxylic acid tert-butyl ester 

Downstream Products

• 1258934-72-3 C₁₁H₇FN₂S 
• 1258934-73-4 5-(4-fluorophenyl)-4H-pyrrolo[2,3-d]thiazole 
• 1258934-81-4 tert-butyl N-{2-chloro-5-[2-(4-fluorophenyl)ethynyl]-1,3-thiazol-4-yl}carbamate 

Relevant academic research and scientific papers

THIAZOLE DERIVATIVES FOR THE TREATMENT OF DISEASES SUCH AS CANCER

Compounds of the formula Ia and Ib, in which R1, R1′, R2, R3, R5, R6 and R7 have the meanings indicated in claim 1, are kinase inhibitors and can be employed, inter alia, for the treatment of tumours.

Novel syntheses of variably substituted pyrrolo[2,3-d]thiazoles

Pyrrolo[2,3-d]thiazoles are conveniently derived from the corresponding o-aminoalkynylthiazoles via microwave assisted 5-endo-dig cyclization. Methylene-bridged substituents in the 6-position are directly obtained from 5-exo-Heck cyclization based on the