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4-[2-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,3,4-thiadiazol-2-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]-butanoic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1258975-66-4

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1258975-66-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1258975-66-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,8,9,7 and 5 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1258975-66:
(9*1)+(8*2)+(7*5)+(6*8)+(5*9)+(4*7)+(3*5)+(2*6)+(1*6)=214
214 % 10 = 4
So 1258975-66-4 is a valid CAS Registry Number.

1258975-66-4Downstream Products

1258975-66-4Relevant academic research and scientific papers

Discovery of Tetrahydropyrazolopyridine as Sphingosine 1-Phosphate Receptor 3 (S1P3)-Sparing S1P1 Agonists Active at Low Oral Doses

Demont, Emmanuel H.,Bailey, James M.,Bit, Rino A.,Brown, Jack A.,Campbell, Colin A.,Deeks, Nigel,Dowell, Simon J.,Eldred, Colin,Gaskin, Pam,Gray, James R. J.,Haynes, Andrea,Hirst, David J.,Holmes, Duncan S.,Kumar, Umesh,Morse, Mary A.,Osborne, Greg J.,Renaux, Jessica F.,Seal, Gail A. L.,Smethurst, Chris A.,Taylor, Simon,Watson, Robert,Willis, Robert,Witherington, Jason

, p. 1003 - 1020 (2016/02/23)

FTY720 is the first oral small molecule approved for the treatment of people suffering from relapsing-remitting multiple sclerosis. It is a potent agonist of the S1P1 receptor, but its lack of selectivity against the S1P3 receptor ha

THIADIAZOLE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DISORDERS MEDIATED BY SLPL RECEPTORS

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Page/Page column 53, (2010/12/31)

The present invention relates to novel compounds having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.

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