1258979-46-2Relevant academic research and scientific papers
Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics
Uramaru, Naoto,Shigematsu, Hidenari,Toda, Akihisa,Eyanagi, Reiko,Kitamura, Shigeyuki,Ohta, Shigeru
experimental part, p. 8727 - 8733 (2011/03/18)
To develop novel nonallergenic pyrazolone analgesics, we synthesized a series of compounds in which position 1 of the pyrazolone ring was substituted in place of the original methyl group in order to block the formation of allergenic metabolites via N-dea
