674-82-8 Usage
Description
Acetyl ketene, also known as diketene, is a colorless liquid with a disagreeable odor. It is slightly less dense than water and has a flash point of 90°F. Acetyl ketene is known to irritate skin and eyes. It is primarily used in the production of paints and pharmaceuticals.
Uses
Used in Paper Industry:
Acetyl ketene is used as a reactant for the manufacture of paper and to control its sizing. It plays a crucial role in enhancing the quality and properties of the final paper product.
Used in Pharmaceutical Industry:
Acetyl ketene is used as a reactant in the preparation of a potent and selective inhibitor of histone methyltransferase EZH2. This inhibitor is particularly effective in the treatment of B-Cell lymphomas, a type of cancer that affects the immune system.
Used in Paint Industry:
Acetyl ketene is utilized in the production of paints, where it contributes to the formation of various paint components and improves their overall performance. Its presence in the paint formulation enhances the paint's durability, adhesion, and other essential properties.
Air & Water Reactions
Highly flammable. Slightly soluble in water.
Reactivity Profile
DIKETENE is a very reactive dimer, Acetyl ketene may undergo a spontaneous decomposition followed by explosion or ignition [Vervalin, 1973, p.86]. In the presence of bases, amines, mineral acids or Lewis acids a violent polymerization will occur, accompanied by gas evolution [Zdenek, F. et al., Czech Pat. 156 584, 1975].
Health Hazard
TOXIC; may be fatal if inhaled, ingested or absorbed through skin. Inhalation or contact with some of these materials will irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Check Digit Verification of cas no
The CAS Registry Mumber 674-82-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,7 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 674-82:
(5*6)+(4*7)+(3*4)+(2*8)+(1*2)=88
88 % 10 = 8
So 674-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C4H4O2/c1-4(6)2-3-5/h2H,1H3
674-82-8Relevant articles and documents
SYNTHESIS OF HIGH CALORIC FUELS AND CHEMICALS
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Paragraph 0070, (2013/05/23)
In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc.
Aktivierung der C-Cl-Bindung: Katalytische Carbonylierung von Dichlormethan und Chlorbenzol
Huser, Marc,Youinou, Marie-Therese,Osborn, John A.
, p. 1427 - 1430 (2007/10/02)
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Preparation and properties of metallacyclobutanes of nickel and palladium
Miyashita, Akira,Ohyoshi, Mayumi,Shitara, Hiroaki,Nohira, Hiroyuki
, p. 103 - 112 (2007/10/02)
Bis(phosphine)-3,3-dimethylnickela- and palladacyclobutanes have been prepared by intramolecular C-H insertion reaction of the corresponding dineopentyl metal complexes.Nickelacyclobutane complexes decompose when heated thereby undergoing competitive carb