1259-10-5

Usage

Uses

Used in Pharmaceutical Industry:
Cycloartenol acetate is used as a potential therapeutic agent for its anti-inflammatory and anti-tumor properties. Its presence in various plant sources makes it a promising candidate for the development of new drugs and treatments for diseases such as cancer and cardiovascular disorders.
Used in Natural Product Chemistry:
Cycloartenol acetate is used as a subject of study in natural product chemistry to explore its potential pharmacological properties and therapeutic applications. Its presence in a wide range of plant species allows researchers to investigate its bioactivity and potential use in drug discovery.
Used in Drug Discovery:
Cycloartenol acetate is used as a starting point for drug discovery due to its potential therapeutic applications and presence in various plant species. Its anti-inflammatory and anti-tumor properties make it a valuable compound for the development of new drugs and treatments for various diseases.

Upstream product

• 21238-33-5 Cycloartenol 
• 469-38-5 cycloartenol 
• 108-24-7 acetic anhydride 
• 127-09-3 sodium acetate 
• 511-63-7 cycloart-24-en-3-one 
• 469-38-5 handianol 

Downstream Products

• 28032-52-2 5α-Lanost-9(11)-en-3β-ol 
• 1180-88-7 3β-acetoxy-5α-lanost-9(11)-ene 
• 4936-10-1 9,19-cyclolanostan-3-one 
• 55724-72-6 3β-acetoxy-lanost-9(11)-en-12-one 
• 6562-14-7 3β-Acethoxy-5α-lanostan 
• 469-38-5 cycloartenol 
• 4575-74-0 cycloartanyl acetate 
• 1180-88-7 δ^9,11-dihydroroylenyl acetate 
• 1724-19-2 δ^8,9-dihydroeupholacetate 
• 4575-74-0 dihydrocycloroylenyl acetate 
• 1180-88-7 24-Dihydroparkeol-acetat 
• 4575-74-0 Acetic acid (3S,9S,13R,14S,17R)-17-((R)-1,5-dimethyl-hexyl)-4,4,13,14-tetramethyl-tetradecahydro-cyclopropa[9,10]cyclopenta[a]phenanthren-3-yl ester 
• 55511-14-3 mangiferonic acid 
• 13878-92-7 mangiferolic acid 

Relevant academic research and scientific papers

3-EPI-CYCLOLAUDENOL AND KNOWN TRITERPENES FROM EUPHORBIA CAUDICIFOLIA

A new tetracyclic triterpene, 3-epi-cyclolaudenol (24-methyl-9,19-cyclolanost-25-en-3α-ol), cyclolaudenol and cycloartenol were isolated from the ethanolic extract of the latex of Euphorbia caudicifolia, and cycloartenol and 3-ketomethylursolate were obtained from the ethanolic extract of the stem of this plant. - Keywords: Euphorbia caudicifolia; Euphorbiaceae; latex; stem; tetracyclic triterpenes; pentacyclic triterpenes; 3-epi-cyclolaudenol; cyclolaudenol; cycloartenol; 3-ketomethylursolate.

Oxyfunctionalization of unactivated C-H bonds in triterpenoids with tert-butylhydroperoxide catalyzed by meso-5,10,15,20-tetramesitylporphyrinate osmium(II) carbonyl complex

A system consisting of meso-5,10,15,20-tetramesitylporphyrinate osmium(II) carbonyl complex [Os(TMP)CO] as a precatalyst and tert-butylhydroperoxide (TBHP) as an oxygen donor is shown to be an efficient, regioselective oxidant system for the allylic oxidation, ketonization and hydroxylation of unactivated C-H bonds in a series of the peracetate derivatives of penta- and tetracyclic triterpenoids. Treatment of the substrates with this oxidant system afforded a variety of novel or scarce oxygenated derivatives in one-step. Structures of the isolated components, after chromatographic separation, were determined by spectroscopic methods including GC-MS and shift-correlated 2D-NMR techniques. Factors governing the regioselectivity and the possible mechanism for the oxyfunctionalization of the unactivated carbons are also discussed.

Conformational Analysis of Cycloartenol, 24-Methylenecycloartanol and Their Derivatives

A conformational analysis of cycloartenol, 24-methylenecycloartenol and their derivatives was carried out in the solution and the solid state by an NMR study and X-ray crystallographic analysis, respectively.Complete assignments of the 1H NMR spectra of these compounds were made in order to elucidate the conformation involving the ring system and side chain.Rings A to C had a chair-halfchair-boat conformation, and the side chain had a zig-zag conformation.

BIOSYNTHESIS OF SITOSTEROL, CYCLOARTENOL, AND 24-METHYLENECYCLOARTANOL IN TISSUE CULTURES OF HIGHER PLANTS AND ERGOSTEROL IN YEAST FROM -AND 2H3>-ACETATE AND 2H2>MVA

The -methyl migrations postulated in the 'biogenetic isoprene rule' proposed by Ruzicka et al. have been verified by (13)C n.m.r. spectroscopy in the biosynthesis of cycloartenol (10a), 24-methylenecycloartenol (11a), and sitosterol (12a) using cultured cells of higher plants, Rabdosia japonica and Physalis peruviana, and of ergosterol (14a) in yeast fed with acetate.The -hydride shifts from C-17 to C-20, and C-13 to C-17 have also been demonstrated in the biosynthesis of sitosterol (12b) in R. japonica and of ergosterol (14b) in yeast fed with acetate.THe -hydride shift from C-9 to C-8 has also been verified in 24-methylenecycloartanol (11b) fed acetate to tissue cultures of Trichosanthes kirilowii Maxim. var. japonica.In the side-chain formation of 24-methylenecycloartanol (11b) and ergosterol (14b), a -hydride (deuteride) shift from C-24 to C-25 is observed.Conversely, no deuterium atom at C-24 or C-25 is observed in sitosterol (12b) formation.Both C-11 and C-12 of sitosterol (12c) labelled as(13)C-(2)H2 and (13)C-(2)H(1)H, biosynthesized from MVA in R. japonica suggest that squalene is released from an enzyme and the following oxidation does not distinguish a terminal double bond of one farnesyl moiety from the other to form epoxysqualenes (8A) and (8B).