1259302-03-8Relevant articles and documents
Synthesis of berberineefflux pump inhibitor hybrid antibacterials
Bremner, John B.,Kelso, Michael J.
, p. 3561 - 3568 (2011/03/17)
This article describes the compact synthesis of two isomeric dual-action hybrid antimicrobials where the 13-position of the antibacterial berberine has been linked via 3′-and 4′-methylene bridges to INF55 (5-nitro-2-phenylindole), an inhibitor of the bacterial NorA multidrug-resistance pump. Copyright Taylor & Francis Group, LLC.