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Upstream product

• 766-98-3 1-ethynyl-4-fluorobenzene 
• 99333-34-3 N-(2,2,2-trifluoroethylidene)-4-methoxyaniline 
• 1361190-52-4 C₁₇H₁₃F₄NO 

Relevant academic research and scientific papers

An efficient synthesis of 2-trifluoromethyl quinolines via gold-catalyzed cyclization of trifluoromethylated propargylamines

A highly efficient cyclization reaction of trifluoromethylated propargylamines leading to 2-trifluoromethyl-4-aryl quinolines was developed by using gold(I) as a catalyst under extremely mild conditions.

Synthesis of 2-trifluoromethyl quinoline by the reaction of fluorinated imine with alkyne catalyzed by indium(III) triflate

Preparation of 2-trifluoromethyl-4-aryl quinolines from a variety of readily available alkynes and N-aryl trifluoroethylimine has been achieved via indium(III) triflate catalyzed Diels-Alder reactions. Georg Thieme Verlag Stuttgart New York.