1259374-37-2Relevant academic research and scientific papers
Structure-based approach to nanomolar, water soluble matrix metalloproteinases inhibitors (MMPIs)
Attolino, Emanuele,Calderone, Vito,Dragoni, Elisa,Fragai, Marco,Richichi, Barbara,Luchinat, Claudio,Nativi, Cristina
, p. 5919 - 5925 (2010)
N-Arylsulfonyl-based MMPs inhibitors (MMPIs) are among the most prominent inhibitors possessing nanomolar affinity. However, their poor bioavailability remains critical for the drug development of this family of molecules. The structural analysis of the c
