1259388-06-1Relevant articles and documents
Zinc(II)-catalyzed Mannich-type reactions of hydrazones with difluoroenoxysilane and its application in the synthesis of optically active 2,2-difluoro-3-oxo-benzohydrazide
Yuan, Zhiliang,Wei, Yin,Shi, Min
, p. 1709 - 1716 (2010)
With the catalysis of Zn(OTf)2, Mannich-type reactions of various aromatic hydrazones 1 with difluoroenoxysilane 2 proceeded smoothly to produce 2,2-difluoro-3-oxo-benzohydrazides in 27%-78% yields in THF or DCM under mild conditions. An unexpe