1259488-10-2

Basic information

• Product Name: C₁₆H₁₁ClF₃N
• CAS NO: 1259488-10-2
• Molecular Weight: 309.718
• Mol File: 1259488-10-2.mol

Chemical Properties

• CAS DataBase Reference: C₁₆H₁₁ClF₃N(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₁₁ClF₃N(1259488-10-2)
• EPA Substance Registry System: C₁₆H₁₁ClF₃N(1259488-10-2)

Safety Data

• Hazardous Substances Data: 1259488-10-2(Hazardous Substances Data)

Upstream product

• 26686-10-2 4,7-dihydro-1H-indole 
• 321-37-9 4'-chloro-2,2,2-trifluoroacetophenone 

Relevant articles and documents

Chiral Bronsted acid-catalyzed enantioselective friedel-crafts reaction of 4,7-dihydroindoles with trifluoromethyl ketones

In the presence of chiral phosphoric acid, an enantioselective Friedel-Crafts reaction of 4,7-dihydroindoles with aromatic trifluoromethyl ketones and ethyl 4,4,4-trifluoroacetoacetate has been realized. A series of 2-substituted 4,7-dihydroindoles with a trifluoromethylated tertiary alcohol moiety were obtained in 45-95% yields with 60-93% ee. Furthermore, 2-functionalized indole derivatives could be produced through a one-pot process.