125950-34-7Relevant academic research and scientific papers
Regiocontrolled Cyclohexenone Annulation via Acylation of a Ketone Carbonyl
Paquette, Leo A.,Ra, Choon Sup,Edmonson, Scott D.
, p. 2443 - 2445 (2007/10/02)
1-(1-Ethoxyvinyl)cycloalkenes, readily available by palladium-catalyzed condensation of enol triflates with ethyl vinyl ether or its α-trimethylstannyl derivative, enter into Diels-ALder reaction with (Z)-1,2-bis(phenylsulfonyl)ethylene.These adducts unde
Palladium-Catalyzed Coupling Reactions of (α-Ethoxyvinyl)trimethylstannane with Vinyl and Aryl Triflates
Kwon, Hyok Boong,McKee, Blain H.,Stille, J. K.
, p. 3114 - 3118 (2007/10/02)
The palladium-catalyzed cross-coupling reaction of vinyl triflates and halides with (α-ethoxyvinyl)trimethylstannane gives high yields of 2-ethoxy 1,3-dienes, which can be hydrolyzed to the corresponding α,β-unsaturated ketones.Aryl triflates undergo an analogous coupling reaction, providing a facile method for replacing the hydroxyl group of a phenol by an acyl group.The use of (α-ethoxyvinyl)trimethylstannane in palladium-catalyzed carbonylative coupling gives rise to vinyl and aryl α-ethoxyvinyl ketones and indirectly to the corresponding α-diketones (which result from their hydrolysis) and glyoxylates (which result from their ozonolysis).
