1259557-04-4

Basic information

• Product Name: C₁₈H₁₈N₂O₈
• CAS NO: 1259557-04-4
• Molecular Weight: 390.35
• Mol File: 1259557-04-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₈N₂O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₈N₂O₈(1259557-04-4)
• EPA Substance Registry System: C₁₈H₁₈N₂O₈(1259557-04-4)

Safety Data

• Hazardous Substances Data: 1259557-04-4(Hazardous Substances Data)

Upstream product

• 59-92-7 levodopa 
• 18766-66-0 (2S,4E)-4-(2-oxoethylidene)-1,2,3,4-tetrahydropyridine-2,6-dicarboxylic acid 

Relevant articles and documents

In vitro synthesis of betaxanthins using recombinant DOPA 4,5-dioxygenase and evaluation of their radical-scavenging activities

Betalamic acid, the chromophore of betaxanthins, was enzymatically synthesized on a large scale from l-dihydroxyphenylalanine (L-DOPA) using recombinant Mirabilis jalapa DOPA 4,5-dioxygenase. After synthesis, proline was directly added to the concentrated reaction mixture to generate proline-betaxanthin. The molecular mass and nuclear magnetic resonance spectrum of the purified product were identical to those previously reported for proline-betaxanthin. Twenty-four betaxanthin species were synthesized by the condensation reaction of purified betalamic acid and amino acids or amines. An HPLC protocol was established for identifying the different betaxanthin species. Proline-, dopamine-, and γ-aminobutyric acid (GABA)-betaxanthins were prepared as representative betaxanthins under large-scale conditions, and their 1,1-diphenyl-2-picrylhydrazyl radical-scavenging activities were compared against those of known antioxidants. GABA-betaxanthin showed comparatively low activity, whereas dopamine-betaxanthin had similar activity to the red pigment betanin and the anthocyanin cyanidin 3-glucoside. Proline-betaxanthin had the highest activity of the three synthesized compounds and was similar to the flavonoid quercetin.