125973-34-4

Basic information

• Product Name: 2,6-di-tert-butyl-4-(methoxyphenyl)-1-naphthalenecarboxylate
• Synonyms: 2,6-di-tert-butyl-4-(methoxyphenyl)-1-naphthalenecarboxylate
• CAS NO: 125973-34-4
• Molecular Weight: 390.522
• Mol File: 125973-34-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,6-di-tert-butyl-4-(methoxyphenyl)-1-naphthalenecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-di-tert-butyl-4-(methoxyphenyl)-1-naphthalenecarboxylate(125973-34-4)
• EPA Substance Registry System: 2,6-di-tert-butyl-4-(methoxyphenyl)-1-naphthalenecarboxylate(125973-34-4)

Safety Data

• Hazardous Substances Data: 125973-34-4(Hazardous Substances Data)

Upstream product

• 68039-43-0 1,3-di-tert-butyl-5-methoxybenzene 
• 879-18-5 naphthalene-1-carbonic acid chloride 

Downstream Products

• 129633-47-2 cis-2,6-bis(tert-butyl)-4-methoxyphenyl 2-butyl-1,2-dihydro-1-naphthalenecarboxylates 
• 129633-47-2 trans-2,6-bis(tert-butyl)-4-methoxyphenyl 2-butyl-1,2-dihydro-1-naphthalenecarboxylate 
• 129633-48-3 cis-2,6-bis(tert-butyl)-4-methoxyphenyl 2-methyl-1,2-dihydro-1-naphthalenecarboxylate 
• 129633-48-3 trans-2,6-bis(tert-butyl)-4-methoxyphenyl 2-methyl-1,2-dihydro-1-naphthalenecarboxylate 
• 129633-49-4 cis-2,6-bis(tert-butyl)-4-methoxyphenyl 2-phenyl-1,2-dihydro-1-naphthalenecarboxylate 
• 129633-49-4 trans-2,6-bis(tert-butyl)-4-methoxyphenyl 2-phenyl-1,2-dihydro-1-naphthalenecarboxylate 
• 99797-48-5 trans-2-phenyl-1,2-dihydro-1-naphthalenylmethanol 
• 99797-48-5 (1R,2S)-(+)-trans-1-(Hydroxymethyl)-2-phenyl-1,2-dihydronaphthalene 
• 99797-53-2 (1S,2R)-(2-phenyl-1,2-dihydronaphthyl)methan-1-ol 
• 125973-37-7 (1RS,2RS)-1-methyl-2-phenyl-1,2-dihydro-1-naphthalenylmethanol 
• 125973-41-3 (1S,2S)-2-Butyl-1-methyl-1,2-dihydro-naphthalene-1-carboxylic acid 2,6-di-tert-butyl-4-methoxy-phenyl ester 
• 6057-87-0 1-methyl-2-phenylnaphthalene 

Relevant articles and documents

A one-flask synthesis of dihydronaphthalenemethanols by directed addition of organolithium reagents to BHA naphthalenecarboxylates

The 1,4-addition reaction of organolithium reagents with 2,6-bis(tert- butyl)-4-methoxyphenyl naphthalenecarboxylates gave regioselectively substituted dihydronaphthalenecarboxylates in high yields. Successive treatment of the esters with organolithiums in THF, lithium triethylborohydride, methyl iodide, and finally sodium borohydride in methanol, provided vegio- and stereoselectively the corresponding 1,1,2- and 1,2,2-trisubstituted dihydronaphthalenylmethanols in good yields. This one- flask process is constituted from a sequence of five reactions involving a reductive generation of an aldehyde metal enolate from a ketene as the key step.